How concussions may disrupt testosterone levels long after the initial brain injury

If your energy, drive or focus feels off and you’ve taken hard hits over the years, your testosterone could be part of the story. A 2025 Wayne State University School of Medicine study is drawing attention to how a shaken brain can suppress the hormone long after the injury, and why athletes and former players may be especially vulnerable. Hormones from the brain’s pituitary gland tell the testes to produce testosterone, and a feedback loop keeps levels in balance, according to Harvard Health. “When testosterone levels rise too high, the brain sends signals to the pituitary to reduce production,” Harvard Health explains.

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